Growth of influenza A viruses in hamsters
Identifieur interne : 002851 ( Main/Exploration ); précédent : 002850; suivant : 002852Growth of influenza A viruses in hamsters
Auteurs : H. Abou-Donia [Royaume-Uni] ; R. Jennings [Royaume-Uni] ; C. W. Potter [Royaume-Uni]Source :
- Archives of Virology [ 0304-8608 ] ; 1980-06-01.
English descriptors
- Teeft :
- Attenuated, Attenuation, Clone, Embryonated, Embryonated eggs, Hamster, Hamster lung, Influenza, Influenza virus, Influenza virus strains, Influenza viruses, Mutant, Parent strain, Parent strains, Parent virus, Present study, Recombinant, Recombinant influenza viruses, Recombinant virus, Recombinant viruses, Recombination, Replication, Respective parent viruses, Temperaturesensitive mutants, Titre, Turbinate, Turbinate homogenates, Vaccine, Virology, Virus, Virus replication, Virus strains.
Abstract
Summary: The growth characteristics of four temperature-sensitive or cold-adapted recombinant influenza viruses and eight recombinant influenza viruses derived in other ways, together with the wild-type, parent viruses of these strains, were tested in hamster lungs and turbinates and in embryonated eggs at different temperatures for their replicative ability. The results showed that although the temperature-sensitive and cold-adapted recombinant viruses replicated to considerably lower titres than their wild-type parent virus strains in hamster lung and at 37° C in embryonated eggs, no similar pattern of growth was observed for the group of A/PR8 and A/Okuda recombinant influenza viruses studied in these systems. The hamster model is not therefore generally applicable as a marker for attenuated influenza virus vaccine strains.
Url:
DOI: 10.1007/BF01317321
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 001101
- to stream Istex, to step Curation: 001101
- to stream Istex, to step Checkpoint: 001465
- to stream Main, to step Merge: 002998
- to stream Main, to step Curation: 002851
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Growth of influenza A viruses in hamsters</title><author><name sortKey="Abou Donia, H" sort="Abou Donia, H" uniqKey="Abou Donia H" first="H." last="Abou-Donia">H. Abou-Donia</name></author><author><name sortKey="Jennings, R" sort="Jennings, R" uniqKey="Jennings R" first="R." last="Jennings">R. Jennings</name></author><author><name sortKey="Potter, C W" sort="Potter, C W" uniqKey="Potter C" first="C. W." last="Potter">C. W. Potter</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:43EB7204A13877F1355EF6C573F4385B4E6014DB</idno><date when="1980" year="1980">1980</date><idno type="doi">10.1007/BF01317321</idno><idno type="url">https://api.istex.fr/ark:/67375/1BB-DHRBT9KH-H/fulltext.pdf</idno><idno type="wicri:Area/Istex/Corpus">001101</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">001101</idno><idno type="wicri:Area/Istex/Curation">001101</idno><idno type="wicri:Area/Istex/Checkpoint">001465</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">001465</idno><idno type="wicri:doubleKey">0304-8608:1980:Abou Donia H:growth:of:influenza</idno><idno type="wicri:Area/Main/Merge">002998</idno><idno type="wicri:Area/Main/Curation">002851</idno><idno type="wicri:Area/Main/Exploration">002851</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Growth of influenza A viruses in hamsters</title><author><name sortKey="Abou Donia, H" sort="Abou Donia, H" uniqKey="Abou Donia H" first="H." last="Abou-Donia">H. Abou-Donia</name><affiliation wicri:level="2"><country>Royaume-Uni</country><placeName><region type="country">Angleterre</region></placeName><wicri:cityArea>Department of Virology, Academic Division of Pathology, University of Sheffield Medical School, Sheffield</wicri:cityArea></affiliation></author><author><name sortKey="Jennings, R" sort="Jennings, R" uniqKey="Jennings R" first="R." last="Jennings">R. Jennings</name><affiliation wicri:level="2"><country>Royaume-Uni</country><placeName><region type="country">Angleterre</region></placeName><wicri:cityArea>Department of Virology, Academic Division of Pathology, University of Sheffield Medical School, Sheffield</wicri:cityArea></affiliation></author><author><name sortKey="Potter, C W" sort="Potter, C W" uniqKey="Potter C" first="C. W." last="Potter">C. W. Potter</name><affiliation wicri:level="2"><country>Royaume-Uni</country><placeName><region type="country">Angleterre</region></placeName><wicri:cityArea>Department of Virology, Academic Division of Pathology, University of Sheffield Medical School, Sheffield</wicri:cityArea></affiliation></author></analytic><monogr></monogr><series><title level="j">Archives of Virology</title><title level="j" type="abbrev">Archives of Virology</title><idno type="ISSN">0304-8608</idno><idno type="eISSN">1432-8798</idno><imprint><publisher>Springer-Verlag</publisher><pubPlace>Vienna</pubPlace><date type="published" when="1980-06-01">1980-06-01</date><biblScope unit="volume">65</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="99">99</biblScope><biblScope unit="page" to="107">107</biblScope></imprint><idno type="ISSN">0304-8608</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0304-8608</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="Teeft" xml:lang="en"><term>Attenuated</term><term>Attenuation</term><term>Clone</term><term>Embryonated</term><term>Embryonated eggs</term><term>Hamster</term><term>Hamster lung</term><term>Influenza</term><term>Influenza virus</term><term>Influenza virus strains</term><term>Influenza viruses</term><term>Mutant</term><term>Parent strain</term><term>Parent strains</term><term>Parent virus</term><term>Present study</term><term>Recombinant</term><term>Recombinant influenza viruses</term><term>Recombinant virus</term><term>Recombinant viruses</term><term>Recombination</term><term>Replication</term><term>Respective parent viruses</term><term>Temperaturesensitive mutants</term><term>Titre</term><term>Turbinate</term><term>Turbinate homogenates</term><term>Vaccine</term><term>Virology</term><term>Virus</term><term>Virus replication</term><term>Virus strains</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Summary: The growth characteristics of four temperature-sensitive or cold-adapted recombinant influenza viruses and eight recombinant influenza viruses derived in other ways, together with the wild-type, parent viruses of these strains, were tested in hamster lungs and turbinates and in embryonated eggs at different temperatures for their replicative ability. The results showed that although the temperature-sensitive and cold-adapted recombinant viruses replicated to considerably lower titres than their wild-type parent virus strains in hamster lung and at 37° C in embryonated eggs, no similar pattern of growth was observed for the group of A/PR8 and A/Okuda recombinant influenza viruses studied in these systems. The hamster model is not therefore generally applicable as a marker for attenuated influenza virus vaccine strains.</div></front></TEI><affiliations><list><country><li>Royaume-Uni</li></country><region><li>Angleterre</li></region></list><tree><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Abou Donia, H" sort="Abou Donia, H" uniqKey="Abou Donia H" first="H." last="Abou-Donia">H. Abou-Donia</name></region><name sortKey="Jennings, R" sort="Jennings, R" uniqKey="Jennings R" first="R." last="Jennings">R. Jennings</name><name sortKey="Potter, C W" sort="Potter, C W" uniqKey="Potter C" first="C. W." last="Potter">C. W. Potter</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/H2N2V1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002851 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 002851 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= H2N2V1
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:43EB7204A13877F1355EF6C573F4385B4E6014DB
|texte= Growth of influenza A viruses in hamsters
}}
| This area was generated with Dilib version V0.6.33. |  |